Health Library

Rickettsialpox

Rickettsia akari

Rickettsialpox is a disease spread by a mite. It causes a chickenpox-like rash on the body.

I Would Like to Learn About:

Causes

Rickettsialpox is caused by the bacteria, Rickettsia akari. It is commonly found in the United States in New York City and other city areas. It also has been seen in Europe, South Africa, Korea, and Russia.

The bacteria are spread by the bite of a mite that lives on mice.

Symptoms

The disease begins at the site of the mite bite as a painless, firm, red lump (nodule). The nodule develops into a fluid-filled blister that bursts and crusts over. This lump may be up to 1 inch (2.5 centimeters) wide. These lumps usually appear on the face, trunk, arms, and legs. They do not appear on the palms of hands and soles of feet. Symptoms usually develop 6 to 15 days after coming in contact with the bacteria.

Other symptoms may include:

• Discomfort in bright light (photophobia)
• Fever and chills
• Headache
• Muscle pain
• Rash that looks like chickenpox
• Sweating
• Runny nose
• Sore throat
• Cough
• Enlarged lymph nodes
• Loss of appetite
• Nausea or vomiting

The rash is not painful and usually clears within a week.

Exams and Tests

The health care provider will do an examination to look for a rash similar to the one in chickenpox.

If rickettsialpox is suspected, these tests will likely be done: 

• Complete blood count (CBC)
• Tests of blood serum (serologic studies)
• Swabbing and culture of the rash

Treatment

The goal of treatment is to cure the infection by taking antibiotics. Doxycycline is the drug of choice. Treatment with antibiotics shortens the duration of symptoms usually to 24 to 48 hours.

Without treatment, the disease usually resolves within 7 to 10 days.

Outlook (Prognosis)

A full recovery is expected when antibiotics are taken as instructed.

Possible Complications

There are usually no complications if the infection is treated.

When to Contact a Medical Professional

Contact your provider if you or your child has symptoms of rickettsialpox.

Prevention

Controlling mice helps prevent the spread of rickettsialpox.

Related Information

References

Elston DM. Bacterial and rickettsial diseases. In: Callen JP, Jorizzo JL, Zone JJ, Piette WW, Rosenbach MA, Vleugels RA, eds. Dermatological Signs of Systemic Disease. 5th ed. Philadelphia, PA: Elsevier; 2017:chap 32.

Fournier P-E, Raoult D. Rickettsia akari (Rickettsialpox). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 187.

Review Date: 7/28/2022  

Reviewed By: Charles I. Schwartz MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

A.D.A.M., Inc. is accredited by URAC, for Health Content Provider (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics. This site complies with the HONcode standard for trustworthy health information: verify here.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- 2024 A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.