Health Library

Atovaquone (By mouth)

Atovaquone (a-TOE-va-kwone)

Treats and prevents pneumonia.

Brand Name(s):

Mepron

When This Medicine Should Not Be Used:

How to Use This Medicine:

Liquid, Tablet

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• This medicine should be taken with food to help your body absorb it. Tell your doctor if you are not able to do this.
• Oral liquid:
  • Foil pouch: Put the contents directly in your mouth or use a dosing spoon or cup. Use 1 pouch for a 5-milliliter (mL) dose. Use 2 pouches for a 10-mL dose.
  • Bottle: Shake the bottle gently before each use.Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
• Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how atovaquone works. Tell your doctor if you are using any of the following:
  • Indinavir
  • Rifabutin
  • Rifampin
  • Tetracycline

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or stomach or bowel problems.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Fever

If you notice these less serious side effects, talk with your doctor:

• Diarrhea
• Headache
• Runny or stuffy nose

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024