Drug Notes - Pramipexole (By mouth) | Lima Memorial Health System

Pramipexole (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to pramipexole.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
You may take this medicine with or without food. Taking this medicine with food may help reduce nausea.
Swallow the extended-release tablet whole. Do not crush, break, or chew it.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose:
- Regular tablet: Skip the missed dose, and take your next dose as usual. Do not take extra medicine to make up for a missed dose.
- Extended-release tablet: If it is less than 12 hours since your missed dose, take the missed dose as soon as you remember and take your next dose at the normal time. If it is more than 12 hours since your missed dose, skip the missed dose and take your next dose at the normal time.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some medicines can affect how pramipexole works. Tell your doctor if you are using the following:
- Amantadine, cimetidine, cisplatin, diltiazem, levodopa, metoclopramide, procainamide, quinidine, quinine, ranitidine, thiothixene, triamterene, verapamil
- Phenothiazine medicine (including chlorpromazine, perphenazine, promethazine, prochlorperazine, thioridazine)
Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
Do not drink alcohol while you are using this medicine.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, low blood pressure, a sleep disorder, or dyskinesia (trouble with muscle control).
This medicine may cause the following problems:
- Low blood pressure
- Hallucinations
- Unusual changes in thoughts or behavior, including an urge to gamble, spend money, binge eat, or an increased sex drive
- Posture changes that you cannot control
- Rhabdomyolysis (muscle disease that can lead to kidney problems)
This medicine may make you dizzy or drowsy. It may even cause you to fall asleep without warning while you drive, talk, or eat. Do not drive or do anything that could be dangerous until you know how this medicine affects you. Stand up slowly if you feel dizzy or lightheaded.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Change in how much or how often you urinate, or painful urination
Changes in vision
Chest pain or trouble breathing
Extreme sleepiness or drowsiness
Fever, confusion, memory problems, sweating, tiredness, trouble sleeping, unusual thoughts or behavior
Lightheadedness, dizziness, or fainting
Muscle pain, stiffness, tenderness, or weakness
Seeing, hearing, or feeling things that are not really there
Twitching or muscle movements you cannot control, tremors, problems with balance or walking

Last Updated: 9/6/2024