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Amphotericin B cholesteryl sulfate complex (By injection)

Amphotericin B Cholesteryl Sulfate Complex (am-foe-TER-i-sin B koe-les-TEER-il SUL-fate KOM-plex)

Treats infections caused by a fungus.

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.
• Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how amphotericin B works. Tell your doctor if you are taking any of the following:
  • Corticotropin, cyclosporin, digoxin, pentamidine, or tacrolimus
  • Antibiotic medicine, cancer medicine, a corticosteroid (such as prednisone or cortisone), or other antifungal medicine

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.
• Your doctor may want to test your blood while you are receiving this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Change in how much or how often you urinate
• Fast heartbeat
• Fever and chills
• Lightheadedness or fainting
• Severe nausea and vomiting
• Trouble breathing

If you notice these less serious side effects, talk with your doctor:

• Swelling, pain, or redness near where the IV needle is given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024