Health Library

Trimethobenzamide (By injection)

Trimethobenzamide (trye-meth-oh-BENZ-a-mide)

Treats nausea and vomiting.

Brand Name(s):

Tigan

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
• Drink plenty of fluids while you are using this medicine to keep from becoming dehydrated.
• A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.
• You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
• You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
• Use a new needle and syringe each time you inject your medicine.
• Never share your medicine with anyone.

If a dose is missed:

• If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose.
• Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

• If you store this medicine at home, keep it at room temperature, away from heat and direct light.
• Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
• Keep all medicine away from children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are using any medicines that make you sleepy (such as sleeping pills, cold and allergy medicine, narcotic pain relievers, or sedatives).
• Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding.
• This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
• If your vomiting does not stop after taking this medicine for one day, call your doctor.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
• Dark-colored urine or pale stools
• Hot, dry skin without sweating
• Lightheadedness or fainting
• Problems with balance or walking
• Seizures
• Uncontrollable muscle movements or twitching
• Yellow skin or eyes
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Blurred vision
• Headache
• Mild diarrhea
• Muscle cramps
• Pain, stinging, burning, redness, or swelling where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024