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Imiglucerase (By injection)

Imiglucerase (im-i-GLOO-ser-ase)

Treats type 1 Gaucher disease.

Brand Name(s):

Cerezyme

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to imiglucerase.

How to Use This Medicine:

Injectable

Your doctor will prescribe your dose and schedule. This medicine is given through an IV placed in a vein. It must be given slowly, so the IV will have to remain in place for 1 to 2 hours.
A nurse or other health provider will give you this medicine.
You may receive other medicines (including allergy medicine, steroid medicine) to help prevent allergic reactions to this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
This medicine may cause infusion-related reactions, which can be life-threatening.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Bluish-colored skin, warmth or redness in your face, neck, arms, or upper chest
Chest pain, trouble breathing
Fast, pounding, or uneven heartbeat
Fever, chills, cough, headache
Lightheadedness, dizziness, fainting
Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

Back pain
Diarrhea, nausea, vomiting, stomach pain
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Tiredness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024

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