Galsulfase (By injection)
Galsulfase (gal-SUL-fase)
Improves walking and stair-climbing ability in people with an enzyme deficiency.
Brand Name(s):
Naglazyme
There may be other brand names for this medicine.When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you have had an allergic reaction to galsulfase.How to Use This Medicine:
Injectable
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the IV will remain in place for at least 4 hours.
- A nurse or other health provider will give you this medicine.
- You may also receive medicines (including allergy medicine, fever medicine) 30 to 60 minutes before starting treatment with this medicine.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart disease, or lung disease. Tell your doctor if you snore or have sleep apnea.
- This medicine may cause the following problems:
- Kidney problems
- Infusion reactions
- Spinal or cervical cord compression (SCC)
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Back pain, trouble moving arms or legs, loss of bladder or bowel control
- Change in how much or how often you urinate
- Chest pain, trouble breathing
- Fever or chills, headache
- Lightheadedness, dizziness, or fainting
- Rapid weight gain, swelling in your hands, ankles, or feet
- Sleepiness
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Cough, sore throat, ear pain, runny or stuffy nose
- Diarrhea, nausea, vomiting, stomach pain
- Joint or muscle pain
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
- Tiredness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 9/6/2024
