Health Library

Icatibant (By injection)

Icatibant (eye-KA-ti-bant)

Treats sudden attacks of hereditary angioedema (HAE).

Brand Name(s):

Firazyr, Sajazir

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. This medicine is usually injected in the abdomen or stomach.
• A nurse or other health provider will give you this medicine.
• You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
• Use a new needle and syringe each time you inject your medicine.
• Wash your hands with soap and water before and after using this medicine.
• The liquid in the prefilled syringe should be clear and colorless. If the liquid is cloudy, discolored, or contains particles, do not use it. Choose another syringe.
• Do not inject into an area that is bruised, painful, or swollen.
• If your symptoms come back or do not get better, you may use another dose, but you must wait at least 6 hours after the first dose. Do not use this medicine more than 3 times in 24 hours.
• Store this medicine in the refrigerator or at room temperature, in the original carton. Do not freeze.
• Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines and foods affect how icatibant works. Tell you doctor if you are also using an ACE inhibitor.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding
• If your throat swells, go to the nearest hospital or emergency clinic after you use this medicine.
• This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

If you notice these less serious side effects, talk with your doctor:

• Redness, pain, itching, burning, bruising, warmth, or swelling where the shot is given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024