Health Library

Margetuximab-cmkb (By injection)

Margetuximab-cmkb (mar-je-TUX-i-mab - cmkb)

Treats breast cancer

Brand Name(s):

Margenza

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through an IV placed in a vein.
• You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
• Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how margetuximab-cmkb works. Tell your doctor if you are using an anthracycline medicine.

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Use an effective form of birth control during treatment with this medicine and for at least 4 months after the last dose.
• Tell your doctor if you are breastfeeding, or if you have heart disease.
• This medicine may cause the following problems:
  • Heart problems
  • Infusion-related reactions
• Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain, trouble breathing, uneven heartbeat
• Fever, chills, cough, dizziness, headache, joint or muscle pain, nausea, vomiting
• Rash, redness, pain, swelling, bleeding, or blisters on the palms of your hands or soles of your feet
• Rapid weight gain, swelling in your hands, ankles, or feet
• Unusual tiredness or weakness

If you notice these less serious side effects, talk with your doctor:

• Arm or leg pain
• Constipation, diarrhea, loss of appetite, stomach pain
• Hair loss
• Numbness, tingling, or burning pain in your hands, arms, legs, or feet
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024