Health Library

Avacopan (By mouth)

Avacopan (a-va-KOE-pan)

Treats granulomatosis with polyangiitis and microscopic polyangiitis.

Brand Name(s):

Tavneos

When This Medicine Should Not Be Used:

How to Use This Medicine:

Capsule

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• It is best to take this medicine with food or milk.
• Swallow the capsule whole. Do not crush, chew, or open it.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
• Missed dose: Skip the missed dose and take your next regular dose. Do not use extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how avacopan works. Tell your doctor if you are using celecoxib, itraconazole, midazolam, rifampin, or simvastatin.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease (including cirrhosis, hepatitis B or C), weak immune system, or any type of infection.
• This medicine may cause the following problems:
  • Liver problems
  • Serious infections
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bloody or cloudy urine, lower back or side pain, painful urination
• Blurred vision, fast or slow heartbeat, pounding in the ears
• Chest pain, trouble breathing
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow eyes or skin
• Fever, chills, cough, sore throat, body aches

If you notice these less serious side effects, talk with your doctor:

• Diarrhea
• Numbness, tingling, or burning pain in your hands, arms, legs, or feet
• Headache, dizziness
• Tiredness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024