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Ceftobiprole medocaril (By injection)

Ceftobiprole Medocaril (sef-toe-BYE-prole me-DOK-a-ril)

Treats infections caused by bacteria, including acute bacterial skin and skin structure infections (ABSSSI), infections in the bloodstream (bacteremia), and community-acquired bacterial pneumonia (CABP). This medicine is an antibiotic.

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be injected slowly, so your IV will need to stay in place for 2 hours.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or history of seizures.
• This medicine may cause brain or nerve problems, including seizures.
• This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Diarrhea may occur 2 months or more after your treatment ends.
• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bluish skin color, swelling of the foot or leg
• Blurred vision, headache, pounding in the ears, slow or fast heartbeat
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Dry mouth, increased thirst, muscle cramps
• Fever, chills, cough, sore throat, body aches
• Seizures
• Unusual bleeding, bruising, or weakness
• Watery or bloody diarrhea

If you notice these less serious side effects, talk with your doctor:

• Change or loss of taste
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 9/6/2024