Lymphofollicular hyperplasia

Lymphadenopathy; Lymphofollicular hypertrophy

Lymphofollicular hyperplasia is an increase in the number of cells found in lymph node. These follicles contain normal white blood cells called lymphocytes. Your body produces more lymphocytes to help prevent bacteria, viruses, and other types of germs from entering the bloodstream. This may or may not be normal depending on why it occurs.

Open References

References

Winter JN. Approach to the patient with lymphadenopathy or splenomegaly. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 154.

Lymphatic system - illustration
The lymphatic system filters fluid from around cells. It is an important part of the immune system. When people refer to swollen glands in the neck, they are usually referring to swollen lymph nodes. Common areas where lymph nodes can be easily felt, especially if they are enlarged, are the groin, armpits (axilla), above the clavicle (supraclavicular), in the neck (cervical), and the back of the head just above hairline (occipital).
Lymphatic system
illustration

Lymphatic system - illustration
The lymphatic system filters fluid from around cells. It is an important part of the immune system. When people refer to swollen glands in the neck, they are usually referring to swollen lymph nodes. Common areas where lymph nodes can be easily felt, especially if they are enlarged, are the groin, armpits (axilla), above the clavicle (supraclavicular), in the neck (cervical), and the back of the head just above hairline (occipital).
Lymphatic system
illustration

A Closer Look

Talking to your MD

Self Care

Tests for Lymphofollicular hyperplasia

Review Date: 8/26/2023

Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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