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Endocrine glands
     
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Endocrine glands

 

Endocrine glands release (secrete) hormones into the bloodstream.

The endocrine glands include:

  • Adrenal
  • Hypothalamus
  • Islets of Langerhans in the pancreas
  • Ovaries
  • Parathyroid
  • Pineal
  • Pituitary
  • Testes
  • Thyroid
 

Hypersecretion is when an excess of one or more hormone is secreted from a gland. Hyposecretion is when the amount of hormones that are released is too low.

There are many types of disorders that can result when too much or too little of a hormone is released.

Disorders that may be associated with abnormal hormone product from a particular gland include:

Adrenal:

  • Addison disease
  • Adrenogenital syndrome or adrenocortical hyperplasia
  • Cushing syndrome
  • Pheochromocytoma

Pancreas:

  • Diabetes mellitus
  • Hypoglycemia

Parathyroid:

  • Low blood calcium level
  • Tetany (abnormal cramping of muscles)
  • Renal calculi (kidney stones)
  • Excessive loss of minerals from bone (osteoporosis)

Pituitary:

  • Growth hormone deficiency
  • Acromegaly
  • Gigantism
  • Diabetes insipidus
  • Cushing disease
 

Testes and ovaries:

  • Lack of sex development (unclear genitalia)

Thyroid:

  • Congenital hypothyroidism
  • Myxedema
  • Goiter
  • Thyrotoxicosis

 

References

Barrett EJ. Organization of endocrine control. In: Boron WF, Boulpaep EL, eds. Medical Physiology. 3rd ed. Philadelphia, PA: Elsevier; 2017:chap 47.

Melmed S, Auchus RJ, Goldfine AB, et al. Principles of endocrinology. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 1.

Newell-Price JDC, Gibb FW. Endocrinology. In: Penman ID, Ralston SH, Strachan MWJ, Hobson RP, eds. Davidson's Principles and Practice of Medicine. 24th ed. Philadelphia, PA: Elsevier; 2023:chap 20.

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          Review Date: 5/12/2023

          Reviewed By: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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