Lyme disease - erythema migrans

Erythema migrans is the initial lesion of Lyme disease, and often appears at the site of the infecting tick bite. It is a red, enlarging rash, flat or slightly raised, and may reach from 4 to 20 inches (12 to 35 cm) across (the average rash is 6 inches, or 17 cm). (Image courtesy of the Centers for Disease Control and Prevention.)