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Swollen lymph nodes

Swollen glands; Glands - swollen; Lymph nodes - swollen; Lymphadenopathy

 

Lymph nodes are present throughout your body. They are an important part of your immune system. Lymph nodes help your body recognize and fight germs, infections, and other foreign substances.

The term "swollen glands" refers to enlargement of one or more lymph nodes. The medical name for swollen lymph nodes is lymphadenopathy.

In a child, a lymph node is considered enlarged if it is more than 1 centimeter (0.4 inch) wide.

Considerations

 

 

Common areas where the lymph nodes can be felt (with the fingers) include:

  • Groin
  • Armpit
  • Neck (there is a chain of lymph nodes on either side of the front of the neck, both sides of the neck, and down each side of the back of the neck)
  • Under the jaw and chin
  • Behind the ears
  • On the back of the head

 

Causes

 

Infections are the most common cause of swollen lymph nodes. Infections that can cause them include:

  • Abscessed or impacted tooth
  • Ear infection
  • Colds, flu, and other infections
  • Swelling (inflammation) of gums (gingivitis)
  • Mononucleosis
  • Mouth sores
  • Sexually transmitted illness (STI)
  • Tonsillitis
  • Tuberculosis
  • Skin infections

Immune or autoimmune disorders that can cause swollen lymph nodes are:

  • HIV
  • Rheumatoid arthritis (RA)

Cancers that can cause swollen lymph nodes include:

  • Leukemia
  • Hodgkin disease
  • Non-Hodgkin lymphoma

Many other cancers may also cause swollen lymph nodes.

Certain medicines can cause swollen lymph nodes, including:

  • Seizure medicines, such as phenytoin
  • Typhoid immunization

Which lymph nodes are swollen depends on the cause and the body parts involved. Swollen lymph nodes that appear suddenly and are painful are usually due to injury or infection. Slow, painless swelling may be due to cancer or a tumor.

 

Home Care

 

Painful lymph nodes are generally a sign that your body is fighting an infection. The soreness usually goes away in a couple of days without treatment. The lymph node may not return to its normal size for several weeks.

 

When to Contact a Medical Professional

 

Contact your health care provider if:

  • Your lymph nodes do not get smaller after several weeks or they continue to get larger.
  • They are red and tender.
  • They feel hard, irregular, or fixed in place.
  • You have fever, night sweats, or unexplained weight loss.
  • Any node in a child is larger than 1 centimeter (0.4 inch) in diameter.

 

What to Expect at Your Office Visit

 

Your provider will perform a physical examination and ask about your medical history and symptoms. Examples of questions that may be asked include:

  • When the swelling began
  • If the swelling came on suddenly
  • Whether any lymph nodes are painful when pressed

The following tests may be done:

  • Blood tests, including liver function tests, kidney function tests, and CBC with differential
  • Lymph node biopsy
  • Chest x-ray
  • CT scan of the abdomen

Treatment depends on the cause of the swollen nodes.

 

 

Open References

References

Tower RL, Camitta BM. Lymphadenopathy. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 517.

Winter JN. Approach to the patient with lymphadenopathy or splenomegaly. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 154.

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  • Lymphatic system

    Lymphatic system

    illustration

  • Infectious mononucleosis

    Infectious mononucleosis

    illustration

  • Circulation of lymph

    Circulation of lymph

    illustration

  • Lymphatic system

    Lymphatic system

    illustration

  • Swollen glands

    Swollen glands

    illustration

  • Lymph tissue in the head and neck

    Lymph tissue in the head and neck

    illustration

    • Lymphatic system

      Lymphatic system

      illustration

    • Infectious mononucleosis

      Infectious mononucleosis

      illustration

    • Circulation of lymph

      Circulation of lymph

      illustration

    • Lymphatic system

      Lymphatic system

      illustration

    • Swollen glands

      Swollen glands

      illustration

    • Lymph tissue in the head and neck

      Lymph tissue in the head and neck

      illustration

    A Closer Look

     

      Talking to your MD

       

        Self Care

         

          Tests for Swollen lymph nodes

           
           

          Review Date: 2/8/2024

          Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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